Enantioselective synthesis of a trans-ethenyl-hydrindene, a useful steroidCD-ring diene precursor

Authors
Di Filippo, M Izzo, I Vece, A De Riccardis, F Sodano, G
Citation
M. Di Filippo et al., Enantioselective synthesis of a trans-ethenyl-hydrindene, a useful steroidCD-ring diene precursor, TETRAHEDR L, 42(6), 2001, pp. 1155-1157
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
6
Year of publication
2001
Pages
1155 - 1157
Database
ISI
SICI code
0040-4039(20010205)42:6<1155:ESOATA>2.0.ZU;2-#
Abstract
A highly efficient enantioselective synthesis of protected trans-hydrindeno l diene 1 is described starting from the readily available Hajos-Parrish ke tone. The reported methodology represents the most convenient route (10 ste ps, 31% overall yield) to both enantiomeric forms of a steroid (estrogenic) CD-ring diene precursor. (C) 2001 Published by Elsevier Science Ltd.