Multicentric lymphosarcoma in a dog with multiple-site skeletal involvement

In this report the authors describe an unusual clinical presentation of lym phosarcoma (LSA) in a dog. A 9-year-old, neutered male, Golden Retriever wa s presented with a primary complaint of sudden onset of tetraparesis, Routi ne survey radiographs revealed multiple-site bony lesions and the histology revealed a diagnosis of LSA with diffuse skeletal and soft tissue involvem ent. The dog responded poorly to medical management and was euthanized on d ay two due to poor prognosis. Malignant I,SA of the bone is a rare extranod al clinicopathologic entity and presents both a diagnostic and therapeutic hurdle. Reports of this kind are sparse and currently no optimal treatment for this entity has been determined.