Adsorption of acridine drugs on silver: surface-enhanced resonance Raman evidence of the existence of different adsorption sites

Authors
Rivas, L Murza, A Sanchez-Cortes, S Garcia-Ramos, JV
Citation
L. Rivas et al., Adsorption of acridine drugs on silver: surface-enhanced resonance Raman evidence of the existence of different adsorption sites, VIB SPECTR, 25(1), 2001, pp. 19-28
Citations number
27
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
VIBRATIONAL SPECTROSCOPY
ISSN journal
09242031 → ACNP
Volume
25
Issue
1
Year of publication
2001
Pages
19 - 28
Database
ISI
SICI code
0924-2031(20010218)25:1<19:AOADOS>2.0.ZU;2-4
Abstract
The adsorption of the acridine derivative drugs Quinacrine (QA) and 9-amino acridine (9AA) on silver surfaces was comparatively studied by surface-enha nced Raman spectroscopy (SERS). The effects of the excitation wavelength, p H and chloride concentration on the SERS spectra were investigated. The ana lysis of the Raman spectra reveals that each drug is able to interact with the metal surface through different mechanisms of adsorption. This is relat ed to the distinct chemical structure of both drugs. The results shown in t his work demonstrate the existence of different adsorption sites on the met al surface. (C) 2001 Elsevier Science B.V. All rights reserved.