A. Gueiffier et al., SYNTHESIS, STRUCTURE AND REACTIVITY OF IMIDAZO[1,2-ALPHA][1,8]NAPHTHYRIDINES, Journal of heterocyclic chemistry, 34(3), 1997, pp. 765-771
The synthesis and reactivity of imidazo[1,2-a][1,8]naphthyridines are
reported. Electrophilic substitution reactions were studied and the si
te of the reaction was established with the aid of high-field H-1 and
C-13 nmr spectra. The experimental C-1 position reaction was correlate
d with a CNDO/2 calculations.