THE SYNTHESIS OF AZAHOMOTRYPTOPHANE DERIVATIVES, THE TRANSFORMATION OF N-TRIFLUOROACETYL-5-BROMO-4-OXONORVALINE METHYL-ESTER INTO 4-(IMIDAZO[1,2-A]AZINYL-3)-4-OXOHOMOALANINE DERIVATIVES

Authors
SKOF M SVETE J STANOVNIK B
Citation
M. Skof et al., THE SYNTHESIS OF AZAHOMOTRYPTOPHANE DERIVATIVES, THE TRANSFORMATION OF N-TRIFLUOROACETYL-5-BROMO-4-OXONORVALINE METHYL-ESTER INTO 4-(IMIDAZO[1,2-A]AZINYL-3)-4-OXOHOMOALANINE DERIVATIVES, Journal of heterocyclic chemistry, 34(3), 1997, pp. 853-856
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
34
Issue
3
Year of publication
1997
Pages
853 - 856
Database
ISI
SICI code
0022-152X(1997)34:3<853:TSOADT>2.0.ZU;2-D
Abstract
Azatryptophane homologues, 4-(imidazo[1,2-a]pyridinyl-3)-9a-9f and 4-( imidazo[1,2-a]pyrimidinyl-3)-4-oxohomoalanine alanine derivatives 9g-9 i, were prepared from N,N-dimethyl-N'-(pyridinyl-2)- 6a-6f and N,N-dim ethyl-N'-(pyrimidinyl-2)formamidines 6g-6i, and (S)-N-trifluoroacetyl- 5-bromo-4-oxonorvaline methyl ester (2) and its (R,S)-isomer.