METHANETRICARBOXYLATES AS KEY REAGENTS FOR THE SIMPLE PREPARATION OF HETEROARYLCARBOXAMIDES WITH POTENTIAL BIOLOGICAL-ACTIVITY .1. REACTIONOF METHANETRICARBOXYLATES WITH INDOLINE AND 1,2,3,4-TETRAHYDROQUINOLINE

Authors
KUTYREV A KAPPE T
Citation
A. Kutyrev et T. Kappe, METHANETRICARBOXYLATES AS KEY REAGENTS FOR THE SIMPLE PREPARATION OF HETEROARYLCARBOXAMIDES WITH POTENTIAL BIOLOGICAL-ACTIVITY .1. REACTIONOF METHANETRICARBOXYLATES WITH INDOLINE AND 1,2,3,4-TETRAHYDROQUINOLINE, Journal of heterocyclic chemistry, 34(3), 1997, pp. 969-972
Citations number
44
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
34
Issue
3
Year of publication
1997
Pages
969 - 972
Database
ISI
SICI code
0022-152X(1997)34:3<969:MAKRFT>2.0.ZU;2-F
Abstract
The reaction of methanetricarboxylates 2a,b with indoline as well as 1 ,2,3,4-tetrahydroquinoline yields tricyclic 4-hydroxy-2(1H)-quinolones with an ester group in position 3 (3, 8a,b). These heterocyclic ester s condense with primary aliphatic, aromatic, and heteroaromatic amines to give the corresponding amides 5a-e and 10a-t.