Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line

Authors
Peinnequin, A Piriou, A Mathieu, J Dabouis, V Sebbah, C Malabiau, R Debouzy, JC
Citation
A. Peinnequin et al., Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line, BIOELECTRO, 51(2), 2000, pp. 157-161
Citations number
14
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOELECTROCHEMISTRY
ISSN journal
03024598 → ACNP
Volume
51
Issue
2
Year of publication
2000
Pages
157 - 161
Database
ISI
SICI code
0302-4598(200006)51:2<157:NEOC2G>2.0.ZU;2-L
Abstract
Non-thermal effects of microwaves (MWs) are one of the main issues studied for revising standards. The effects of MW exposure on apoptosis at non-ther mal level (48 h, 2.45 GHz, 5 mW/cm(2)) have been studied. Results obtained assess non-thermal MW effects on Fas, but neither on butyrate- nor on ceram ide-induced apoptosis in human Jurkat T-cell line. These data show that MW interacts either with Fas pathway between receptor and caspase-3 activation or on membrane proteins (i.e. Fas receptor or neurosphyngomyelinase). (C) 2000 Elsevier Science S.A. All rights reserved.