Postoperative mortality in patients with liver cirrhosis undergoing transurethral resection of the prostate: a Danish nationwide cohort study

Objective To examine the risk of 30-day postoperative mortality from transu rethral resection of the prostate (TURP) in patients with liver cirrhosis, who are reportedly at considerably increased perioperative risk. Patients and methods For the period 1 January 1977 to 31 December 1993, a p opulation-based cohort was identified comprising Danish patients diagnosed with liver cirrhosis and a random sample of Danes also undergoing TURP. Log istic regression models were used to estimate the association between liver cirrhosis, age, type of admission, comorbidity and 30-day mortality. Results In a cohort of 23 133 patients with liver cirrhosis, 30 underwent T URP; 150 controls with no liver cirrhosis also underwent the same procedure . Of the patients with liver cirrhosis, 6.7% died within 30 days of TURP; t he estimated adjusted odds ratio was 3.0 (95% confidence interval 0.4-22.9) for the 30-day postoperative mortality in patients with liver cirrhosis co mpared with patients without (mortality 2%). Advanced age, comorbidity and acute admission seemed to be associated with an increased postoperative mor tality. Conclusion This study indicates that TURP in patients with liver cirrhosis was associated with increased mortality.