Four patients with AL amyloidosis treated with high-dose chemotherapy and autologous stem cell transplantation

Citation
G. Reich et al., Four patients with AL amyloidosis treated with high-dose chemotherapy and autologous stem cell transplantation, BONE MAR TR, 27(3), 2001, pp. 341-343
Citations number
12
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
27
Issue
3
Year of publication
2001
Pages
341 - 343
Database
ISI
SICI code
0268-3369(200102)27:3<341:FPWAAT>2.0.ZU;2-V
Abstract
Four patients with AL amyloidosis underwent high-dose chemotherapy and auto logous stem cell transplantation at our institutions. Here, we report the c linical courses and outcomes in these patients. Two patients with multiorga n amyloid deposits including cardiac involvement died within 12 days after high-dose chemotherapy. However, in the other two patients, one of whom was suffering from amyloid-related cardiac failure, a significant improvement of organ function was achieved,