The case of a patient with progressive acromegaly and a toxic multinod
ular goiter is reported. The spectrum of thyroid disorders that can oc
cur in association with acromegaly is reviewed. Diffuse goiter, thyroi
d nodules, and thyroid cancer are common in patients with acromegaly.
Peripheral hyperthyroidism, usually due to toxic nodules, has also bee
n reported, IGF 1 elevation may play a key role in the pathogenesis of
thyroid disorders associated with acromegaly. Routine investigations
for thyroid disorders are warranted in patients with acromegaly.