The purpose of this study was to determine the possible causes, clinical fi
ndings, and associated complications of pneumomediastinum in children, Medi
cal records from January 1985 to December 1994 were retrospectively reviewe
d at Children's Hospital Medical Center of Akron using International Classi
fication of Diseases, ninth revision, codes to identify cases of pneumomedi
astinum, The medical causes, nontraumatic and noniatrogenic, of pneumomedia
stinum were studied; intubated or trauma patients and patients having under
gone procedures were excluded. Neonates were also excluded. Twenty-nine cas
es of pneumomediastinum were identified. Two patients (7%) had recurrent pn
eumomediastinum. Only the first episode of pneumomediastinum was included i
n the data analysis. Twenty males (69%) and nine females (31%) were affecte
d, The most common medical causes of pneumomediastinum were asthma exacerba
tions (17/59%) and infections (8/28%). Over the 10-year period, the prevale
nce of pneumomediastinum in children with asthma exacerbations was 0.2% (21
/10,472); 1% (1/126) in children with airway foreign bodies and 0.2% (1/351
) in children with esophageal foreign bodies. The most common signs and sym
ptoms were subcutaneous emphysema (22/76%), sore throat or neck pain (11/38
%), and Hamman's crunch (3/10%), The most common complication was pneumotho
rax with small pneumothoraces in 2 patients (7%) and a tension pneumothorax
in I asthmatic with recurrent pneumomediastinum. Patients without sore thr
oat or neck pain and patients admitted to the intensive care unit had great
er hospital lengths of stay. Pneumomediastinum appears to be uncommon in ch
ildren, The most common medical causes were asthma and infections, The most
common signs and symptoms were subcutaneous emphysema, sore throat or neck
pain, and Hamman's crunch. The most common complication was pneumothorax,
The clinical significance of pneumomediastinum is its cause and association
with significant complications.