Numerical simulation of flow oscillations in stenotic arterial segment

Citation
A. Tura et S. Cavalcanti, Numerical simulation of flow oscillations in stenotic arterial segment, COMPUT BIOL, 31(2), 2001, pp. 113-131
Citations number
38
Categorie Soggetti
Multidisciplinary
Journal title
COMPUTERS IN BIOLOGY AND MEDICINE
ISSN journal
00104825 → ACNP
Volume
31
Issue
2
Year of publication
2001
Pages
113 - 131
Database
ISI
SICI code
0010-4825(200103)31:2<113:NSOFOI>2.0.ZU;2-5
Abstract
The hypothesis that stenosis-induced flow disturbances may be the cause of vascular sounds was investigated. The onset of flow oscillations in a vesse l with a severe constriction was simulated by a computer model based on the axi-symmetric Navier-Stokes equations. Model includes fluid non-linear ine rtial forces, viscoelastic wall motion, anatomical taper and proximal and d istal circulation. Self-excited flow oscillations with different oscillator y patterns were reproduced. A common characteristic of such flow oscillatio ns was a high-frequency component in the audible band (100-500 Hz). Numeric al results support the hypothesis that vascular sounds may be generated by high-frequency flow oscillations. (C) 2001 Elsevier Science Ltd. All rights reserved.