The hypothesis that stenosis-induced flow disturbances may be the cause of
vascular sounds was investigated. The onset of flow oscillations in a vesse
l with a severe constriction was simulated by a computer model based on the
axi-symmetric Navier-Stokes equations. Model includes fluid non-linear ine
rtial forces, viscoelastic wall motion, anatomical taper and proximal and d
istal circulation. Self-excited flow oscillations with different oscillator
y patterns were reproduced. A common characteristic of such flow oscillatio
ns was a high-frequency component in the audible band (100-500 Hz). Numeric
al results support the hypothesis that vascular sounds may be generated by
high-frequency flow oscillations. (C) 2001 Elsevier Science Ltd. All rights
reserved.