Protein arrays and microarrays

Authors
Citation
H. Zhu et M. Snyder, Protein arrays and microarrays, CURR OP C B, 5(1), 2001, pp. 40-45
Citations number
33
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN journal
13675931 → ACNP
Volume
5
Issue
1
Year of publication
2001
Pages
40 - 45
Database
ISI
SICI code
1367-5931(200102)5:1<40:PAAM>2.0.ZU;2-3
Abstract
In the past, studies of protein activities have focused on studying a singl e protein at a time, which is often time-consuming and expensive. Recently, with the sequencing of entire genomes, large-scale proteome analysis has b egun. Arrays of proteins have been used for the determination of subcellula r localization, analysis of protein-protein interactions and biochemical an alysis of protein function. New protein-microarray technologies have been i ntroduced that enable the high-throughput analysis of protein activities. T hese have the potential to revolutionize the analysis of entire proteomes.