H. Santacruz et S. Vriz, REGIONAL DISTRIBUTION OF MATERNAL MESSENGER-RNA SOX-19 IN THE ZEBRAFISH EARLY EMBRYO, Biology of the cell, 88(3), 1996, pp. 153-155
Asymmetric distribution of mRNA has been associated with polarisation
and cell fate determination during early development of animal embryos
. In this report we determine the distribution pattern of Zf-Sox 19 mR
NA during early embryogenesis of zebrafish. Zf-Sox 19 mRNA is found in
one pole of the embryo at the 8-cell stage and in the deep cell layer
close to the yolk, perhaps under the influence of yolk determinants.
Zf-Sox 19 is the earliest gene in zebrafish development whose RNA show
s a restricted localisation. This result indicates that the first eigh
t blastomeres are not equivalent in their molecular components.