Asymmetric Pauson-Khand reactions of chiral sulfinamides: Asymmetric synthesis of 3-azabicyclo[3.3.0]oct-5-en-7-one derivatives

Authors
Hiroi, K Watanabe, T
Citation
K. Hiroi et T. Watanabe, Asymmetric Pauson-Khand reactions of chiral sulfinamides: Asymmetric synthesis of 3-azabicyclo[3.3.0]oct-5-en-7-one derivatives, HETEROCYCLE, 54(1), 2001, pp. 73-76
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
54
Issue
1
Year of publication
2001
Pages
73 - 76
Database
ISI
SICI code
0385-5414(20010101)54:1<73:APROCS>2.0.ZU;2-1
Abstract
Unprecedented asymmetric Pauson-Khand reactions of chiral sulfinamides are described. Cobalt-catalyzed reactions of chiral N-allyl-N-propargyl-N-aryls ulfinamide derivatives were carried out in dichloromethane at -20 degreesC similar to room temperature under carbon monoxide atmosphere in the presenc e of Co-2(CO)(8) to give chiral 3-azabicyclo[3.3.0]oct-5-en-7-one with mode rate or low enantioseleotivity.