M. Somei et al., Syntheses of Wasabi phytoalexin (methyl 1-methoxyindole-3-carboxylate) andits 5-iodo derivative, and their nucleophilic substitution reactions, HETEROCYCLE, 54(1), 2001, pp. 425-432
A simple synthetic method for methyl 1-methoxyindole-3-carboxylate, a phyto
alexin isolated from Wasabia japonica, syn. Eutrema wasabi, and its 5-iodo
derivative is reported. They underwent nucleophilic substitution reactions
selectively at the 2-position.