Infliximab for the treatment of orofacial Crohn's disease

Authors
Mahadevan, U Sandborn, WJ
Citation
U. Mahadevan et Wj. Sandborn, Infliximab for the treatment of orofacial Crohn's disease, INFLAMM B D, 7(1), 2001, pp. 38-42
Citations number
28
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
INFLAMMATORY BOWEL DISEASES
ISSN journal
10780998 → ACNP
Volume
7
Issue
1
Year of publication
2001
Pages
38 - 42
Database
ISI
SICI code
1078-0998(200102)7:1<38:IFTTOO>2.0.ZU;2-S
Abstract
Orofacial manifestations of Crohn's disease can be difficult to diagnose an d treat. We report a case in which the orofacial lesions occurred 7 years p rior to the diagnosis of underlying inflammatory bowel disease. The patient was refractory to mesalamine and systemic corticosteroids but responded to infliximab, the chimeric monoclonal antibody to tumor necrosis factor (TNF -alpha). A review of the literature of the orofacial granulomatoses is pres ented as well.