We report the first case of repaglinide-induced factitious hypoglycemia in
a young male. This case posed a challenging diagnostic dilemma because comm
ercial assays for repaglinide are not available. Furthermore, the patient h
ad a series of positive diagnostic tests such as high proinsulin and locali
zing intra-arterial calcium stimulation suggestive of insulinoma. This case
, again, demonstrates the importance of pure clinical judgment in the face
of often-conflicting laboratory data in making a correct diagnosis and the
requirement of definitive data for an appropriate therapeutic resolution.