Relations among measures of trait anxiety, depression, panic, somatization,
alcohol use, drug use, and treatment for depression were investigated beca
use, typically, studies (a) addressed relations among subsets of only 2 or
3 of the measures and (b) dealt almost exclusively with narrow samples of t
he population representing extremes on 1 or 2 of the measures. In this stud
y, relations among all 7 measures were assessed with participants represent
ing a wide range of scores on all the measures. The 369 participants (155 m
en, 214 women) were sampled from the general population. Three replications
of the same study consistently yielded hypothesized positive intercorrelat
ions among all 7 scales. Factor 1 (Anxiety-Depression) included Trait Anxie
ty, Depression, and Panic scales. Factor 2 (Substance Abuse) included Drug
Use, Alcohol Use, Treatment for Depression, and Somatization scales. Factor
2 highlighted self-medication as a defining characteristic of somatizers a
nd corroborated findings showing that substance abuse is often a precursor
to treatment for depression-like symptoms that can be ameliorated with abst
inence. Factors 1 and 2 were significantly intercorrelated (r = .41, df = 3
67, p < .05), showing a 17% shared variance in two common groupings of psyc
hological dysfunction (anxiety-depression, substance abuse) in the general
population. Thus, depending on socioeconomic and demographic variables, a t
hird common form of dysfunction in the general population is represented by
a combination of anxiety-depression plus substance abuse.