Alternating copoly(ester amide)s derived from amino alcohols and L-tartaric and succinic acids

A set of copoly(ester amides (s-PEASTn) containing equal amounts of amide a nd eater groups has been synthesized from succinic and tartaric acids, and aliphatic linear amino alcohols with 2, 3 and 6 carbon atoms. : in these mi xed poly(ester amide)s the amino alcohol unit adopts a syndioregic orientat ion and the succinic and tartaric units alternate regularly along the polym er chain. These compounds were characterized by elemental analysis, SEC and FT-IR and H-1/C-13 NMR spectroscopy. s PEASTn are stereoregular polymers w hich display optical activity in solution and are crystalline in the solid State with melting points between 90 and 160 degreesC. They all are non-wat er soluble at room temperature but take up water in amounts up to 30% of th eir weights when exposed to a humid atmosphere.