In comparison with most medical imaging techniques, Nuclear Medical imaging
has traditionally been plagued by inferior image quality as a result of th
e limitations imposed by mechanical collimation, which is necessary to form
an image using single-photon emitters. To a large extent, this basic limit
ation may be overcome with the use of posit;on-emitting radiotracers to det
ect the two photons that are emitted following positron annihilation. Altho
ugh CdZnTe semiconductor detectors are renowned for their increased count-r
ate capabilities and improved energy and spatial resolution, they have some
limitations regarding timing and charge collection efficiency. The CdZnTe
rise-time has two components: electrons, and hole-induced charge collection
; Since the holes move much slower than the electrons, and because there is
an equal absorption probability at all depths and energies(in the region o
f 511 keV), the different slopes between the rise rime and the timing signa
l, vary dramatically. These slopes are mostly influenced by the 'small pixe
l effect'. This effect is relative to the amount of charge collected and th
erefore, a different pulse shape slope will be obtained for different charg
es collected. The current study directly examines the timing limitations of
measuring coincidence events in CdZnTe-pixelated detectors. The results sh
ow that it is possible to use these detectors for positron emission applica
tions. (C) 2001 Elsevier Science B.V. All rights reserved.