We study experimentally statistical properties of the opening times of knot
s in vertically vibrated granular chains. Our measurements are in good qual
itative and quantitative agreement with a theoretical model involving three
random walks interacting via hard-core exclusion in one spatial dimension.
In particular, the knot survival probability follows a universal scaling f
unction which is independent of the chain length, with a corresponding diff
usive characteristic time scale. Both the large-exit-time and the small-exi
t-time tails of the distribution are suppressed exponentially, and the corr
esponding decay coefficients ore in excellent agreement with theoretical va
lues.