Liposarcoma of the lung is extremely ran with only 11 cases previously
reported. A case of a locally advanced pulmonary pleomorphic liposarc
oma in a 49-year-old male is presented. Surgery was performed but radi
cal resection was not possible. Post-operative radiotherapy (40 Gy) wa
s given concurrently with cisplatin (12.5 mg daily for 10 days), A par
tial response of short duration was obtained. The patient died 8 month
s following surgery with disseminated disease. Based on reports in the
literature, liposarcoma of the lung must be classified as an aggressi
ve highly metastatic disease responding poorly to both chemotherapy an
d radiotherapy. (C) 1997 Elsevier Science Ireland Ltd.