CYCLOSPORINE-A IN THE TREATMENT OF NECROBIOSIS LIPOIDICA DIABETICORUM

Authors
DARGENTO V CURATOLI G FILOTICO R FOTI C VENA GA
Citation
V. Dargento et al., CYCLOSPORINE-A IN THE TREATMENT OF NECROBIOSIS LIPOIDICA DIABETICORUM, Journal of dermatological treatment, 8(2), 1997, pp. 123-125
Citations number
26
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Journal of dermatological treatment → ACNP
ISSN journal
09546634
Volume
8
Issue
2
Year of publication
1997
Pages
123 - 125
Database
ISI
SICI code
0954-6634(1997)8:2<123:CITTON>2.0.ZU;2-T
Abstract
We report a case of necrobiosis lipoidica diabeticorum in a 36-year-ol d man suffering from uncompensated diabetes mellitus. The dermatosis w as characterized by dark-red infiltrated patches with protruding perip heral borders located on the lower extremities, the dorsal aspects of the feet and hands, and the trunk. Histologically the lesions showed a palisaded granuloma in the middermis. The patient was treated with or al cyclosporin A (CsA) which resulted in a marked improvement in the c linical picture. The rationale for this therapeutic approach is briefl y discussed.