Mk. Kulshrestha et al., The role of preoperative subconjunctival mydricaine and topical diclofenacsodium 0.1% in maintaining mydriasis during vitrectomy, RETINA, 20(1), 2000, pp. 46-51
Citations number
31
Categorie Soggetti
Optalmology
Journal title
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Purpose: To establish the role of preoperative subconjunctival mydricaine a
nd diclofenac 0.1% in maintaining mydriasis during vitrectomy.
Methods: Fifty-seven patients were entered into the study. All were given c
yclopentolate 1% and phenylephrine 2.5% preoperatively. Each patient was ra
ndomly allocated to one of three groups. In Group 1, patients received mydr
icaine by subconjunctival injection and diclofenac 0.1% topically preoperat
ively. In Group 2, patients received only subconjunctival mydricaine, Group
3 patients received only topical diclofenac preoperatively. Pupil diameter
was measured with calipers before and at the end of the operation.
Results: There was no statistically significant difference in the change in
pupil size between Groups 2 and 3. In all patients in Group 1 (who receive
d both subconjunctival mydricaine and diclofenac preoperatively), pupil siz
e was either maintained or increased after vitrectomy. This result was stat
istically significant when compared with the other groups (for Group 1 vers
us Group 2, P < 0.005; for Group 1 versus Group 3, P < 4.7 X 10(-06)).
Conclusion: Topical diclofenac is useful for maintaining pupil size during
vitrectomy only when used in conjunction with subconjunctival mydricaine, e
specially in patients in whom prolonged surgery is anticipated.