Chemo- and regioselective synthesis of alkyl-3-thiazoline carboxylates

Authors
Fernandez, X Fellous, R Lizzani-Cuvelier, L Loiseau, M Dunach, E
Citation
X. Fernandez et al., Chemo- and regioselective synthesis of alkyl-3-thiazoline carboxylates, TETRAHEDR L, 42(8), 2001, pp. 1519-1521
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
8
Year of publication
2001
Pages
1519 - 1521
Database
ISI
SICI code
0040-4039(20010219)42:8<1519:CARSOA>2.0.ZU;2-V
Abstract
The synthesis of a series of allyl substituted 3-thiazoline-carboxylates wa s carried out from the corresponding thiazolidines, by a MnO2-mediated oxid ation reaction under mild conditions. The reaction was chemoselective towar ds the amine-imine oxidation and was also regioselective, affording the uns aturation at the 3-position of the heterocycle. (C) 2001 Published by Elsev ier Science Ltd.