Model studies for molecular recognition of carbonic anhydrase and carboxypeptidase

Authors
Kimura, E
Citation
E. Kimura, Model studies for molecular recognition of carbonic anhydrase and carboxypeptidase, ACC CHEM RE, 34(2), 2001, pp. 171-179
Citations number
41
Categorie Soggetti
Chemistry & Analysis",Chemistry
Journal title
ACCOUNTS OF CHEMICAL RESEARCH
ISSN journal
00014842 → ACNP
Volume
34
Issue
2
Year of publication
2001
Pages
171 - 179
Database
ISI
SICI code
0001-4842(200102)34:2<171:MSFMRO>2.0.ZU;2-Q
Abstract
Model studies using Zn2+ complexes of various derivatives of macrocyclic tr iamines ([12]aneN(3)) and tetraamines (cyclen) have been found to be useful in elucidating and understanding the intrinsic properties of substrate or inhibitor recognition by zinc ions at the active centers of carbonic anhydr ase and carboxypeptidase.