Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol-dependent patients

Authors
Himmerich, H Anghelescu, I Klawe, C Szegedi, A
Citation
H. Himmerich et al., Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol-dependent patients, ALC ALCOHOL, 36(1), 2001, pp. 26-28
Citations number
23
Categorie Soggetti
Clinical Psycology & Psychiatry","Neurosciences & Behavoir
Journal title
ALCOHOL AND ALCOHOLISM
ISSN journal
07350414 → ACNP
Volume
36
Issue
1
Year of publication
2001
Pages
26 - 28
Database
ISI
SICI code
0735-0414(200101/02)36:1<26:VBAHES>2.0.ZU;2-4
Abstract
Vitamin B12 serum levels and markers for alcohol consumption were determine d in 80 male alcohol-dependent patients. Spearman correlation coefficients (r(S)) were calculated. Significant positive correlations between vitamin B 12 and hepatic enzyme values were found (gamma-glutamyltransferase: r(S) = 0.58; alanine aminotransferase: r(S) = 0.43; aspartate aminotransferase: r( S) = 0.47; glutamate dehydrogenase: r(S) = 0.43; all P < 0.001). Therefore, for a proper interpretation of vitamin B12 levels, it may be clinically re levant to take markers of hepatocellular damage into account.