The relation between glutamine and the immunodepression observed in exercise

Citation
Lm. Castell et Ea. Newsholme, The relation between glutamine and the immunodepression observed in exercise, AMINO ACIDS, 20(1), 2001, pp. 49-61
Citations number
62
Categorie Soggetti
Biochemistry & Biophysics
Journal title
AMINO ACIDS
ISSN journal
09394451 → ACNP
Volume
20
Issue
1
Year of publication
2001
Pages
49 - 61
Database
ISI
SICI code
0939-4451(2001)20:1<49:TRBGAT>2.0.ZU;2-9
Abstract
Glutamine is the most abundant amino acid in the body. It is an important f uel for some key cells of the immune system. Both the plasma concentration of glutamine and the functional ability of immune cells in the blood are de creased after prolonged, exhaustive exercise. Glutamine feeding has had ben eficial effects in clinical situations, and the provision of glutamine afte r intensive exercise has decreased the incidence of infections, particularl y of upper respiratory tract infections. However, the precise effect of glu tamine on immunodepression in this situation is not yet established.