Readiness potential in different states of physical activation and after ingestion of taurine and/or caffeine containing drinks

To investigate the influence of taurine and caffeine containing drinks and physical stress on the cortical movement-preparation, the readiness potenti als or "Bereitschaftspotentiale" (BPs), preceding voluntary self-placed ped alling movements, were examined after different states of exhaustion on an ergometer. 15 (13 right-handed) healthy men, aged between 22-30, participat ed in a randomised, cross over, double-blind, placebo controlled study. BPs were averaged out of artefact free EEG-segments from more than 90 trigg ered events, measured at 17 electrodes of the 10:20 system. With increasing effort the BPs were enlarged differently depending on the drink consumed. In placebo trials after exhaustive exercise premovement negative potential curves could be seen even in frontal areas. With caffeine the BPs increased after lower workload, achieving a level, which was reached in the placebo trials only after submaximal physical activation. Furthermore a significant shortening of premovement-brain-potentials in frontal and parietal regions could be seen in the caffeine trials at rest. Taurine admixture seems to i nhibit this effects.