Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds

Authors
Diehl, G Liesener, A Karst, U
Citation
G. Diehl et al., Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds, ANALYST, 126(3), 2001, pp. 288-290
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYST
ISSN journal
00032654 → ACNP
Volume
126
Issue
3
Year of publication
2001
Pages
288 - 290
Database
ISI
SICI code
0003-2654(2001)126:3<288:LCWPET>2.0.ZU;2-1
Abstract
The first hyphenation of high performance liquid chromatography (HPLC), ele ctrochemical online oxidation and mass spectrometry (MS) is described. Ferr ocenecarboxylic acid esters of various alcohols and phenols have been synth esized, separated by reversed-phase HPLC and oxidized (ionized) coulometric ally prior to single quadrupole MS analysis using electrospray ionization ( ESI) and atmospheric pressure chemical ionization (APCI) interfaces. The de pendence of the ionization on the electrochemical pretreatment is demonstra ted. Limits of detection for selected derivatives range from 4 x 10(-9) to 4 x 10(-7) mol dm(-3) depending on the individual compound and the selected interface.