A total of 76 repeat sperm retrievals were carried out in 47 azoospermic me
n. The outcome of the procedures was evaluated regarding to the interval be
tween two successive procedures. Sperm motility and pregnancy rate were not
increased by increasing the interval between two successive sperm retrieva
ls from less than 90 days to more than 180 days. The pregnancy rate decline
d from 50% with a less than 90-day interval to 25% with a more than 180-day
interval. The trend did not quits reach the significance level. Pregnancy
was obtained in only 27% of the couples where TESE was done the last time a
gainst 48 and 57% where PESA and TESA. respectively, were performed the las
t time (p< .05) This study suggests that sperm retrieval procedures in men
with obstructive azoospermia can be carried out with time intervals of only
3 months to obtain an optimal pregnancy rate, and it might suggest that an
epididymal aspiration procedure should be preferred for a TESE.