A new property of MCM-41: Drug delivery system

Citation
M. Vallet-regi et al., A new property of MCM-41: Drug delivery system, CHEM MATER, 13(2), 2001, pp. 308-311
Citations number
17
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science","Material Science & Engineering
Journal title
CHEMISTRY OF MATERIALS
ISSN journal
08974756 → ACNP
Volume
13
Issue
2
Year of publication
2001
Pages
308 - 311
Database
ISI
SICI code
0897-4756(200102)13:2<308:ANPOMD>2.0.ZU;2-0
Abstract
A new application of MCM-41 mesoporous materials has been developed. Two ki nds of surfactants, C16TAB and C12TAB, have been employed to get different pore sizes. The samples were disk-shaped conformed before and after chargin g with ibuprofen, an antiinflammatory drug. In all the cases the weight per cent ratio of drug/MCM-41 was 30%. The drug release plots show a different behavior depending on the method for charging the drug in the material but not on the employed surfactant.