Objective To examine the relationship between spontaneous abortion and chro
mosomal abnormalities.
Methods Couples who had one or more consecutive spontaneous abortions and h
ad normal genitals were enrolled for cytogenetic karyotype analysis.
Results In the 61 couples, the detected incidence was 11.5%, with five Robe
rtsonian translocations, one reciprocal translocation, and one pericentric
inversion of chromosome 7.
Conclusion Chromosomal abnormalities may play an important role in fetal wa
stage.