We employed enzyme immunoassay (EIA) and Western blotting techniques to mea
sure the level of antibodies to Toxoplasma gondii proteins in serum samples
from 38 individuals undergoing their first episode of schizophrenia and fr
om a group of matched control subjects. We found that the individuals with
first-episode schizophrenia had significantly increased levels of IgG, IgM,
and IgA class antibodies to Toxoplasma proteins, as compared with the cont
rol subjects.