Neuroimaging studies have been conducted with increasing frequency in recen
t years in attempts to identify structural and functional abnormalities in
the brains of persons with attention deficit/hyperactivity disorder. Althou
gh the results of these studies are frequently cited in support of a biolog
ic etiology for this disorder, inconsistencies among studies raise question
s about the reliability of the findings. The present review shows that no s
pecific abnormality in brain structure or function has been convincingly de
monstrated by neuroimaging studies. Implications regarding stimulant treatm
ent for attention deficit/hyperactivity disorder are discussed.