EI-1511-3, EI-1511-5 AND EI-1625-2, NOVEL INTERLEUKIN-1-BETA CONVERTING-ENZYME INHIBITORS PRODUCED BY STREPTOMYCES SP E-1511 AND E-1625 .2.STRUCTURE DETERMINATION
Y. Uosaki et al., EI-1511-3, EI-1511-5 AND EI-1625-2, NOVEL INTERLEUKIN-1-BETA CONVERTING-ENZYME INHIBITORS PRODUCED BY STREPTOMYCES SP E-1511 AND E-1625 .2.STRUCTURE DETERMINATION, Journal of antibiotics, 49(11), 1996, pp. 1079-1084
The structures of three novel interleukin-1 beta converting enzyme inh
ibitors, EI-1511-3, -5 and EI-1625-2 were determined by spectroscopic
methods. Their absolute configurations were also determined by analyse
s of the CD spectra of the inhibitors and their oxidation products wit
h chromium trioxide.