Biologic properties of non-antibiotic, chemically modified tetracyclines (CMTs): A structured, annotated bibliography

The first paper reporting on a potentially important medical property of a non-antimicrobial tetracycline appeared in 1987. Since then, a literature o f over 75 papers has supported the therapeutic potential of this class of c ompounds. in this review, this literature is grouped and organized with com mentary on the data which has been published to date. The biomedical applic ability of these discoveries obviously covers a wide range of medical condi tions and clearly justifies their continued development.