Research and development in biosensors

Citation
Fw. Scheller et al., Research and development in biosensors, CURR OPIN B, 12(1), 2001, pp. 35-40
Citations number
51
Categorie Soggetti
Microbiology
Journal title
CURRENT OPINION IN BIOTECHNOLOGY
ISSN journal
09581669 → ACNP
Volume
12
Issue
1
Year of publication
2001
Pages
35 - 40
Database
ISI
SICI code
0958-1669(200102)12:1<35:RADIB>2.0.ZU;2-E
Abstract
Progress in biosensors has mainly been made by the improvement of the biolo gical components and the implementation of microsystem technologies. Enzyme s are still the most appropriate recognition elements because they combine high chemical specificity and inherent biocatalytic signal amplification. A breakthrough has been achieved in the application of membrane-integrated r eceptor systems for analyte recognition and signal transduction in biosenso rs. Sensor integration of RNA aptamers has been initiated, and the performa nce of fully synthetic molecularly imprinted polymers has been improved.