New developments in microarray technology

Microarrays have emerged as indispensable research tools for gene expressio n profiling and mutation analysis. New classification of cancer subtypes, d issecting the yeast metabolism and large-scale genotyping of human single n ucleotide polymorphisms are important results being obtained with this tech nique. Realizing the microsphere-based massively parallel signature sequenc ing technique as fluid microarrays, building new types of protein arrays an d constructing miniaturized flow-through systems, which can potentially tak e this technology from the research bench into industrial, clinical and oth er routine applications, exemplify the intense developments that are now on going in this field.