S. Di Legge et al., Usefulness of primitive reflexes in demented and non-demented cerebrovascular patients in daily clinical practice, EUR NEUROL, 45(2), 2001, pp. 104-110
The aim of this study was to investigate the usefulness of primitive reflex
es (PRs) as additional alert signs in a routine clinical setting of cogniti
ve decline in an elderly population of chronic ischemic cerebrovascular pat
ients. We considered the occurrence of grasp, palmomental, glabellar and sn
out reflexes in 75 demented (VaD) and 75 non-demented (VaND) patients, and
in 75 healthy elderly controls. We never elicited more than two PRs in cont
rols. The occurrence of three or four PRs provided the strongest correlatio
n with dementia (p < 0.0001), with 93% specificity irrespective of low sens
itivity. In conclusion, the occurrence of more than two PRs might serve as
an additional warning sign of possible mild cognitive impairment in chronic
ischemic cerebrovascular patients, Copyright (C) 2001 S. Karger AG, Basel.