N. Qureshi et al., A randomized controlled trial to assess the psychological impact of a family history screening questionnaire in general practice, FAM PRACT, 18(1), 2001, pp. 78-83
Background. It has been postulated that systematic enquiry about patients'
family histories of inherited illnesses would lead to a population of worri
ed well'.
Objective. The purpose of the present study was to evaluate if the use of a
family history screening questionnaire (FHSQ) as part of a general practic
e health check leads to psychological distress.
Method. We conducted a randomized controlled trial of a self-administered F
HSQ in a single general practice. Individuals who had not had a health chec
k within the previous 2 years were randomized within th ree age group strat
a to intervention group (receiving health check and FHSQ) or control group
(only receiving health check). A total of 156 patients were offered health
checks; 100 accepted and 76 of them were followed th rough to the 3-month e
nd point. Responses to the six-item Spielberger State-Trait Anxiety Invento
ry (STAI), Perception of Health questionnaire and Family History Concern qu
estionnaire were compared between intervention and control groups.
Results. A two-way analysis of variance on the STAI scores 1 and 2 weeks af
ter the health check with baseline scores as a covariate showed that at bot
h times anxiety was higher in the intervention group than in the controls (
F = 6.4; d.f. = 1,73; P = 0.014). Three months later, there was no signific
ant difference between the two groups. The Perception of Health questionnai
re only showed a significant result at 1 week, the intervention group havin
g a more pessimistic response to the question eliciting patient's concerns
about future health (P = 0.025).
Conclusion. Short-term psychological distress due to the family history scr
eening questionnaire was identified but did not persist.