Objective: To determine whether myomectomy during pregnancy in selected pat
ients improves outcome. Methods: Retrospective analysis of 18 patients who
underwent myomectomy between the 6th and 24th week of gestational age. Surg
ical management of tumors was required on the basis of the characteristics
of the myomas and symptoms. The dimensions and site of myomas, symptoms of
the patients, time and mode of delivery, and pregnancy outcome were analyze
d. Results: One woman was lost to follow-up, and one suffered a miscarriage
. The remaining 16 patients delivered healthy babies between the 36th and 4
1st week; 14 delivered by cesarean section, and 2 vaginally. Conclusion: We
suggest that myomectomy during pregnancy may be considered safe in selecte
d patients. Moreover, it permits good pregnancy outcome with healthy babies
delivered at term. Copyright (C) 2001 S. Karger AG, Basel.