Repeat-induced point mutation (RIP) in crosses with wild-isolated strains of Neurospora crassa: Evidence for dominant reduction of RIP

Seventy-one wild-isolated strains of Neurospora crassa were examined for th eir ability to support repeat-induced point mutation (RIP) in the erg-3 loc us. RIP was exceptionally inefficient but detectable in crosses with the st rain FGSC 430 from Adiopodoume, Ivory Coast. We could find no consistent di fferences in ascospore yields when wild isolates identified as "low-RIP" or "high-RIP" strains were crossed with strains bearing the segmental duplica tion Dp(IIIR > [I; II])AR17. This suggested that RIP may not be responsible for the barren phenotype of crosses involving segmental duplication strain s. (C) 2001 Academic Press.