Isolation, physico-chemical properties and structure elucidation studies on HA-2-91, a new tetraene polyene antifungal antibiotic produced by Streptomyces arenae var ukrainiana

Authors
Gupte, TE Chatterjee, NR Nanda, RK Naik, SR
Citation
Te. Gupte et al., Isolation, physico-chemical properties and structure elucidation studies on HA-2-91, a new tetraene polyene antifungal antibiotic produced by Streptomyces arenae var ukrainiana, I J CHEM B, 39(12), 2000, pp. 936-940
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
39
Issue
12
Year of publication
2000
Pages
936 - 940
Database
ISI
SICI code
0376-4699(200012)39:12<936:IPPASE>2.0.ZU;2-M
Abstract
HA-2-91, a new tetraene polyene macrolide antibiotic 1 has been isolated fr om the culture broth of Streptomyces arenae var ukrainiana and purified by silica gel column chromatography followed by preparative TLC. Its structure has been determined on the basis of spectral data (UV, IR, H-1 and C-13 NM R, mass), which accounts for its potent antifungal activity.