Development of a gas chromatographic method for fungicide cymoxanil analysis in dried hops

An analytical method for detecting cymoxanil (2-cyano-N- [(ethylamino)carbo nyl]-2-(methoxyimino)-acetamide) residues in dried hops was developed utili zing liquid-liquid partitioning, automated gel permeation chromatography (G PC), solid phase extraction (SPE) cleanup, and gas chromatography (GC). Met hod validation recoveries from dried hops were 96 +/- 12, 108 +/- 11, and 1 36 +/- 8% over three levels of fortification (0.05, 0.5, and 1.0 ppm, respe ctively). The hop samples from three field sites, which were treated with c ymoxanil, had residue levels ranging from 0.146 to 0.646 ppm. The detection limit and the quantitation limit of the method developed in the present st udy were 0.022 and 0.050 ppm, respectively.