This paper describes a computational and experimental investigation of flow
in a proto-type model geometry, of a fully occluded 45 deg distal end-to-s
ide anastomosis. Previous investigations have considered a similar configur
ation where the centerlines of the bypass and host vessels lie within a pla
ne, thereby producing a plane of symmetry within the flow. We have extended
these investigations by deforming the bypass vessel out of the plane of sy
mmetry, thereby breaking the symmetry of the flow and producing a nonplanar
geometry. Experimental data were obtained using magnetic resonance imaging
of flow within perspex models and computational data were obtained from si
mulations using a high-order spectral/hp element method. We found that the
nonplanar three-dimensional flow notably alters the distribution of wall sh
ear stress at the bed of the anastomosis, reducing the peak wall shear stre
ss peak by approximately 10 percent when compared with the planar model. Fu
rthermore, an increase in the absolute flux of velocity into the occluded r
egion, proximal to the anastomosis, of 80 percent was observed in the nonpl
anar geometry when compared with the planar geometry. [S0148-0731(00)00401-
5].