Objective: To determine the degree of agreement between central venous pres
sure (CVP) and peripheral venous pressure (PVP) in surgical patients.
Design: Prospective study.
Setting: University hospital.
Participants: Patients without cardiac dysfunction undergoing major electiv
e noncardiac surgery (n = 150).
Measurements and Main Results: Simultaneous CVP and PVP measurements were o
btained at random points in mechanically ventilated patients during surgery
(n = 100) and in spontaneously ventilating patients in the postanesthesia
care unit (n = 50). In a subset of 10 intraoperative patients, measurements
were made before and after a 2-L fluid challenge. During surgery, PVP corr
elated highly to CVP (r = 0.86), and the bias (mean difference between CVP
and PVP) was -1.6 +/- 1.7 mmHg (mean +/- SD). In the postanesthesia care un
it, PVP also correlated highly to CVP (r = 0.88), and the bias was -2.2 +/-
1,9 (mean +/- SD). When adjusted by the average bias of -2, PVP predicted
the observed CVP to within +/-3 mmHg in both populations of patients with 9
5% probability. In patients receiving a fluid challenge, PVP and CVP increa
sed similarly from 6 +/- 2 to 11 +/- 2 mmHg and 4 +/- 2 to 9 +/- 2 mmHg.
Conclusion: Under the conditions of this study, PVP showed a consistent and
high degree of agreement with CVP in the perioperative period in patients
without significant cardiac dysfunction. PVP -2 was useful in predicting CV
P over common clinical ranges of CVP. PVP is a rapid noninvasive tool to es
timate volume status in surgical patients. Copyright (C) 2001 by W.B. Saund
ers Company.