Opioid poorly-responsive cancer pain. Part 2: Basic mechanisms that could shift dose response for analgesia

Authors
Mercadante, S Portenoy, RK
Citation
S. Mercadante et Rk. Portenoy, Opioid poorly-responsive cancer pain. Part 2: Basic mechanisms that could shift dose response for analgesia, J PAIN SYMP, 21(3), 2001, pp. 255-264
Citations number
85
Categorie Soggetti
General & Internal Medicine","Neurosciences & Behavoir
Journal title
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
ISSN journal
08853924 → ACNP
Volume
21
Issue
3
Year of publication
2001
Pages
255 - 264
Database
ISI
SICI code
0885-3924(200103)21:3<255:OPCPP2>2.0.ZU;2-N
Abstract
Basic research in experimental pain models may illuminate the phenomenon of cancer pain that is poorly responsive to opioid drugs. Research findings c an be valuable in formulating new strategies in clinical practice. This rev iew evaluated experimental observations in terms of the events that occur i n cancer patients receiving opioid therapy for pain. J Pain Symptom Manage 2001;21:255-264. (C) U.S. Cancer Pain Relief Committee, 2001.