Xenon as neuroprotectant in acute stroke?

Authors
Altschuler, EL
Citation
El. Altschuler, Xenon as neuroprotectant in acute stroke?, MED HYPOTH, 56(2), 2001, pp. 227-228
Citations number
7
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
MEDICAL HYPOTHESES
ISSN journal
03069877 → ACNP
Volume
56
Issue
2
Year of publication
2001
Pages
227 - 228
Database
ISI
SICI code
0306-9877(200102)56:2<227:XANIAS>2.0.ZU;2-P
Abstract
Stroke is one of the most common diseases worldwide. A current focus of res earch is to find neuroprotectants that can be given during acute stroke. On e specific target is to find antagonists of the N-methyl-D-aspartate (NMDA) receptor in an attempt to limit glutamate associated neurotoxicity. Xenon has recently been found to be an NMDA receptor antagonist. I suggest that x enon be considered as a neuroprotectant in acute stroke, and discuss method s of testing this proposal. (C) 2001 Harcourt Publishers Ltd.